What’s the difference between ‘strep throat’ and a sore throat? We’re developing a vaccine for one of them
- Written by: Kim Davis, General paediatrician and paediatric infectious diseases specialist, Murdoch Children's Research Institute
What’s the difference?[1] is a new editorial product that explains the similarities and differences between commonly confused health and medical terms, and why they matter.
It’s the time of the year for coughs, colds and sore throats. So you might have heard people talk about having a “strep throat”.
But what is that? Is it just a bad sore throat that goes away by itself in a day or two? Should you be worried?
Here’s what we know about the similarities and differences between strep throat and a sore throat, and why they matter.
How are they similar?
It’s difficult to tell the difference between a sore throat and strep throat as they look and feel similar.
People usually have a fever, a bright red throat and sometimes painful lumps in the neck (swollen lymph nodes). A throat swab can help diagnose strep throat, but the results can take a few days.
Thankfully, both types of sore throat usually get better by themselves[2].
How are they different?
Most sore throats are caused by viruses such as common cold viruses, the flu (influenza virus), or the virus that causes glandular fever (Epstein-Barr virus).
These viral sore throats can occur at any age. Antibiotics don’t work against viruses so if you have a viral sore throat, you won’t get better faster if you take antibiotics. You might even have some unwanted antibiotic side-effects[3].
But strep throat is caused by Streptococcus pyogenes bacteria, also known as strep A. Strep throat is most common in school-aged children[4], but can affect other age groups. In some cases, you may need antibiotics to avoid some rare but serious complications.
In fact, the potential for complications is one key difference between a viral sore throat and strep throat.
Strep throat is caused by Streptococcus bacteria and can be treated with antibiotics if needed.
Kateryna Kon/Shutterstock[15]
Why do some people get sicker than others?
We know strep A infections and rheumatic heart disease are more common[16] in low socioeconomic communities where poverty and overcrowding lead to increased strep A transmission and disease.
However, we don’t fully understand why some people only get a mild infection with strep throat while others get very sick with invasive disease.
We also don’t understand why some people get rheumatic heart disease after strep A infections when most others don’t. Our research team is trying to find out.
How about a vaccine for strep A?
There is no strep A vaccine but many[17] groups[18] in Australia[19], New Zealand[20] and[21] worldwide[22] are working towards one.
For instance, Murdoch Children’s Research Institute and Telethon Kids Institute have formed the Australian Strep A Vaccine Initiative[23] to develop strep A vaccines. There’s also a global consortium[24] working towards the same goal.
Companies such as Vaxcyte[25] and GlaxoSmithKline[26] have also been developing strep A vaccines.
What if I have a sore throat?
Most sore throats will get better by themselves. But if yours doesn’t get better in a few days or you have ongoing fever, see your GP.
Your GP can examine you, consider running some tests and help you decide if you need antibiotics.
References^ What’s the difference? (theconversation.com)^ by themselves (www.ncbi.nlm.nih.gov)^ antibiotic side-effects (www.ncbi.nlm.nih.gov)^ school-aged children (www.tandfonline.com)^ very unlikely (www.bmj.com)^ chronic fatigue syndrome (www.ncbi.nlm.nih.gov)^ multiple sclerosis (www.science.org)^ cancers (www.thelancet.com)^ rising in recent years (www.who.int)^ around the world (www.ncbi.nlm.nih.gov)^ rheumatic heart disease (www.who.int)^ Around the world (www.nejm.org)^ highest rates (onlinelibrary.wiley.com)^ More than 5,300 (www.aihw.gov.au)^ Kateryna Kon/Shutterstock (www.shutterstock.com)^ are more common (link.springer.com)^ many (www.ncbi.nlm.nih.gov)^ groups (www.ncbi.nlm.nih.gov)^ Australia (www.ncbi.nlm.nih.gov)^ New Zealand (www.ncbi.nlm.nih.gov)^ and (www.ncbi.nlm.nih.gov)^ worldwide (www.clinicalkey.com.au)^ Australian Strep A Vaccine Initiative (www.asavi.org.au)^ global consortium (savac.ivi.int)^ Vaxcyte (www.ncbi.nlm.nih.gov)^ GlaxoSmithKline (www.ncbi.nlm.nih.gov)
